Giuseppe Plazzi Selected Research

Sleep Wake Disorders

1/2022	The orexin story, sleep and sleep disturbances.
11/2021	Increased Serum Prolactin and Excessive Daytime Sleepiness: An Attempt of Proof-of-Concept Study.
1/2021	International Expert Opinions and Recommendations on the Use of Melatonin in the Treatment of Insomnia and Circadian Sleep Disturbances in Adult Neuropsychiatric Disorders.
1/2021	Pre-treatment of blood samples reveal normal blood hypocretin/orexin signal in narcolepsy type 1.
1/2020	Giving a voice to cataplectic experience: recollections from patients with narcolepsy type 1.
2/2018	Increased interferon-mediated immunity following in vitro and in vivo Modafinil treatment on peripheral immune cells.
1/2018	Sodium Oxybate Treatment in Pediatric Type 1 Narcolepsy.
1/2018	Long-term compliance, safety, and tolerability of sodium oxybate treatment in patients with narcolepsy type 1: a postauthorization, noninterventional surveillance study.
6/2014	Narcolepsy as an autoimmune disease: the role of H1N1 infection and vaccination.
7/2013	Nocturnal rapid eye movement sleep latency for identifying patients with narcolepsy/hypocretin deficiency.

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Giuseppe Plazzi Research Topics

Disease

110	Narcolepsy 09/2022 - 08/2003
61	Cataplexy 01/2022 - 08/2003
23	Disorders of Excessive Somnolence (Hypersomnia) 01/2022 - 03/2007
14	Sleep Wake Disorders 01/2022 - 12/2002
11	Sleepiness 09/2022 - 03/2008
10	REM Sleep Behavior Disorder 12/2021 - 05/2013
7	Parkinson Disease (Parkinson's Disease) 01/2022 - 08/2013
7	Synucleinopathies 01/2022 - 01/2017
6	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2022 - 06/2009
5	Hallucinations (Hallucination) 01/2022 - 11/2013
5	Movement Disorders (Movement Disorder) 08/2021 - 12/2011
5	Dementia (Dementias) 01/2021 - 01/2017
5	Sleep Paralysis 01/2020 - 05/2010
5	Restless Legs Syndrome (Restless Legs) 01/2018 - 02/2006
5	Idiopathic Hypersomnia 07/2016 - 11/2009
4	Disease Progression 01/2022 - 12/2011
4	Cognitive Dysfunction 01/2022 - 03/2007
4	Multiple System Atrophy 01/2022 - 01/2017
4	Human Influenza (Influenza) 09/2015 - 12/2013
3	Overweight 01/2022 - 02/2013
3	Mental Disorders (Mental Disorder) 01/2021 - 02/2014
3	Obstructive Sleep Apnea 01/2020 - 01/2010
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 01/2021
2	Mood Disorders (Mood Disorder) 11/2021 - 01/2021
2	Parkinsonian Disorders (Parkinsonism) 10/2021 - 01/2020
2	Weight Loss (Weight Reduction) 01/2021 - 12/2016
2	Schizophrenia (Dementia Praecox) 01/2021 - 02/2014
2	Body Weight (Weight, Body) 01/2020 - 12/2016
2	Prion Diseases (Transmissible Spongiform Encephalopathies) 01/2020 - 12/2002
2	Headache (Headaches) 01/2019 - 01/2018
2	Nausea 01/2019 - 01/2018
2	Epilepsy (Aura) 01/2019 - 01/2019
2	Nasopharyngitis 01/2019 - 01/2018
2	Inflammation (Inflammations) 10/2018 - 06/2011
2	Nervous System Diseases (Neurological Disorders) 09/2015 - 02/2014
2	Obesity 06/2015 - 02/2013
2	Precocious Puberty 06/2015 - 02/2013
1	Breast Neoplasms (Breast Cancer) 01/2022
1	Hypertriglyceridemia 01/2022
1	Paralysis (Palsy) 01/2022
1	Pain (Aches) 01/2022
1	Fatigue 12/2021

Drug/Important Bio-Agent (IBA)

52	OrexinsIBA 01/2022 - 12/2008
22	Sodium Oxybate (gamma Hydroxybutyrate)FDA Link 01/2022 - 01/2010
21	Pharmaceutical PreparationsIBA 09/2022 - 08/2003
14	HLA-DQB1 antigen (HLA DQB1)IBA 01/2022 - 11/2005
12	Biomarkers (Surrogate Marker)IBA 01/2022 - 06/2014
10	N-(4-aminophenethyl)spiroperidol (NAPS)IBA 12/2021 - 03/2008
7	SynucleinsIBA 01/2022 - 05/2017
6	AntibodiesIBA 09/2020 - 08/2009
5	Biological ProductsIBA 01/2022 - 04/2012
5	Antidepressive Agents (Antidepressants)IBA 12/2021 - 01/2016
5	Modafinil (Provigil)FDA Link 12/2021 - 08/2012
5	solriamfetolIBA 12/2021 - 01/2019
4	pitolisantIBA 09/2022 - 01/2020
4	AutoantibodiesIBA 01/2019 - 07/2010
4	pandemrixIBA 01/2019 - 02/2014
4	HLA Antigens (Human Leukocyte Antigens)IBA 06/2015 - 07/2010
3	HDL CholesterolIBA 01/2022 - 11/2009
3	Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric 12/2021 - 01/2016
3	Proteins (Proteins, Gene)FDA Link 01/2021 - 12/2013
3	Orexin ReceptorsIBA 01/2019 - 01/2017
3	SodiumIBA 01/2018 - 11/2012
3	VaccinesIBA 01/2017 - 02/2013
3	Protons (Proton)IBA 12/2012 - 09/2007
2	Peptides (Polypeptides)IBA 01/2022 - 01/2021
2	Mitochondrial DNA (mtDNA)IBA 01/2022 - 03/2006
2	Hypnotics and Sedatives (Sedatives)IBA 12/2021 - 01/2021
2	Clomipramine (Anafranil)FDA LinkGeneric 12/2021 - 01/2021
2	Methylphenidate (Ritalin)FDA LinkGeneric 12/2021 - 01/2021
2	Amphetamine (Amfetamine)FDA LinkGeneric 12/2021 - 01/2021
2	MelatoninIBA 01/2021 - 11/2017
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2020 - 01/2020
2	MethyltransferasesIBA 01/2020 - 01/2020
2	Dopamine (Intropin)FDA LinkGeneric 01/2020 - 01/2020
2	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 01/2020
2	Wakefulness-Promoting AgentsIBA 02/2018 - 01/2016
2	IronIBA 01/2018 - 11/2013
2	AcidsIBA 01/2018 - 05/2017
2	SaltsIBA 01/2018 - 05/2017
2	Immunoglobulin G (IgG)IBA 02/2017 - 08/2009
2	Clonazepam (Rivotril)FDA LinkGeneric 01/2017 - 05/2013
2	Anticonvulsants (Antiepileptic Drugs)IBA 11/2015 - 09/2012
2	HLA-DQA1 antigen (HLA DQA1)IBA 01/2015 - 12/2013
2	EpitopesIBA 07/2014 - 12/2013
2	NeuropeptidesIBA 02/2014 - 09/2009
2	Glucose (Dextrose)FDA LinkGeneric 10/2013 - 11/2009
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2013 - 06/2009
2	N-acetylaspartate (N-acetyl aspartate)IBA 12/2012 - 09/2009
2	streptolysin OIBA 07/2010 - 08/2009
1	melanopsinIBA 01/2022
1	alpha-SynucleinIBA 01/2022
1	Orexin Receptor AntagonistsIBA 01/2022
1	Opioid Analgesics (Opioids)IBA 01/2022

Therapy/Procedure

9	Therapeutics 11/2021 - 10/2008
3	Immunotherapy 08/2021 - 01/2020
2	Aftercare (After-Treatment) 04/2011 - 02/2007
1	Drug Prescriptions 09/2022
1	Knee Replacement Arthroplasty (Total Knee Replacement) 01/2022
1	Hip Replacement Arthroplasty (Total Hip Replacement) 01/2022